Question

. Which statement below is NOT correct?

a. If excessive myc activity would inappropriately cause a cell to overproliferate (as in cancer), p53 can trigger apoptosis by stimulating transcription of Bcl-2
b. Survival factors suppress apoptosis by regulating Bcl-2 family members.
c. Aggregation of procaspases increases the likelihood of their activation.
d. A cell will die unless it receives a signal not to.
e. Bcl-2 family members trigger release of cytochrome c from the sarcoplasmic reticulum

Answer 1

The statement 'e. Bcl-2 family members trigger release of cytochrome c from the sarcoplasmic reticulum' is NOT correct. Bcl-2 family members play a role in controlling the release of cytochrome c from the mitochondria, not the sarcoplasmic reticulum.

Step-by-step explanation:

The statement 'e. Bcl-2 family members trigger release of cytochrome c from the sarcoplasmic reticulum' is NOT correct. Bcl-2 family members play a role in controlling the release of cytochrome c from the mitochondria, not the sarcoplasmic reticulum. During apoptosis, cytochrome c is released from the mitochondria into the cytosol, not from the sarcoplasmic reticulum, and this triggers a series of molecular events leading to apoptosis.