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Which of the following are target of the APC (anaphase promoting complex)?

a. Securins
b. S-Phase cyclin-Ckd inhibitor (p21)
c. G1 cyclins
d. Mitotic cyclins
e. (A) and (D)

User Choasia
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1 Answer

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Final answer:

The target of the APC (anaphase promoting complex) is securins and mitotic cyclins. The APC degrades securins, which prevent sister chromatid separation, and mitotic cyclins, which regulate the cell cycle progression.

Step-by-step explanation:

The target of the APC (anaphase promoting complex) is securins and mitotic cyclins. The correct answer is (E) both (A) and (D). The APC is responsible for degrading securins, which are proteins that prevent sister chromatid separation during anaphase. It also degrades mitotic cyclins, which regulate the progression of the cell cycle. By targeting these proteins for degradation, the APC helps to ensure proper cell division.

User Ehsan Ullah Nazir
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