Question

P21 acts as a:

a. p53 inhibitor
b. DNA polymerase inhibitor
c. Cdk inhibitor
d. Mdm2 inhibitor
e. cyclin inhibitor

Answer 1

p21 acts as a Cdk inhibitor or is controlled by p53. It binds to and inhibits the activity of the Cdk/cyclin complexes, preventing the progression of the cell cycle when there is damaged DNA.

Step-by-step explanation:

p21 acts as a Cdk inhibitor or is controlled by p53. p21 is a protein that enforces the halt in the cell cycle dictated by p53 by binding to and inhibiting the activity of the Cdk/cyclin complexes. This prevents the progression of the cell cycle, especially when there is damaged DNA.