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Large families of membrane proteins contain an interior channel with key _____________ residues at strategic locations that provides an aqueous passageway through the lipid bilayer.

User Karptonite
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Final answer:

Membrane proteins contain hydrophilic channels lined with hydrophilic residues, such as aquaporins, to facilitate the movement of polar substances across the lipid bilayer.

Step-by-step explanation:

Large families of membrane proteins contain hydrophilic channels that facilitate the movement of substances through the impermeable lipid bilayer. The interior channel of these proteins is lined with key hydrophilic residues that provide an aqueous passageway, allowing for the transport of polar compounds and ions. An example of such proteins is aquaporins, which are channel proteins specifically designed to allow water molecules to pass rapidly through the cell membrane, thereby bypassing the nonpolar central layer that would otherwise impede their movement.

User IVoid
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