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What statement about nucleosomes is false?

A. A nucleosome is a "bead" on a string of unfolded chromatin.
B. A nucleosome produces a 3-fold packing ratio of DNA.
C. Nucleosomes are found only in mitotic chromosomes.
D. A nucleosome consists of DNA wrapped around 8 histone proteins, plus a short segment of linker DNA.

1 Answer

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Final answer:

A nucleosome is a structure formed by DNA wrapped around histone proteins. Nucleosomes are present in both mitotic and non-mitotic chromosomes. The false statement is that nucleosomes are found only in mitotic chromosomes.

Step-by-step explanation:

A nucleosome is a structure formed by DNA wrapped around a core of eight histone proteins, with a short segment of linker DNA connecting each nucleosome. This structure gives the appearance of 'beads on a string'.

The 3-fold packing ratio of DNA mentioned in option B is true. It refers to the compaction of DNA in nucleosomes, where the DNA is wrapped around the histone proteins tightly.

Option C is false. Nucleosomes are not found only in mitotic chromosomes. They are present in both mitotic and non-mitotic chromosomes.

Therefore, the false statement about nucleosomes is option C: Nucleosomes are found only in mitotic chromosomes.

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