Final answer:
Histone proteins have a high proportion of positively charged amino acids, which attract the negatively charged phosphate groups on DNA.
Step-by-step explanation:
The true statement about the tight association of histone proteins and DNA is:
A. Histone proteins have a high proportion of positively charged amino acids, which attract the negatively charged phosphate groups on DNA.
The positively charged lysine and arginine amino acids in the histone proteins bind to the negatively charged phosphate groups on DNA, allowing the DNA to wrap around the histone proteins to form nucleosomes. This association helps in the packaging and organization of DNA in the cell nucleus.