Question

In the ER, during the modification of the core oligosaccharide on glycoproteins, two of the three terminal glucose residues are removed. The remaining glucose bonds to an ER chaperone protein called calnexin to help the glycoprotein to fold properly. The remaining glucose is then removed by ________ to release the glycoprotein from the chaperone.

Answer 1

Two of the three terminal glucose residues are removed during the modification of the core oligosaccharide on glycoproteins in the ER. The remaining glucose bonds with an ER chaperone protein to assist with protein folding. An enzyme called glucosidase removes the final glucose residue to release the glycoprotein from the chaperone.

Step-by-step explanation:

During the modification of the core oligosaccharide on glycoproteins in the ER, two of the three terminal glucose residues are removed.

The remaining glucose then bonds to an ER chaperone protein called calnexin to help the glycoprotein fold properly. The final glucose residue is removed by an enzyme called glucosidase to release the glycoprotein from the chaperone.