Question

What provides the energy for DNA polymerization?

A) The hydrolysis of ATP (releasing Pi)
B) The hydrolysis of GTP (releasing Pi)
C) The hydrolysis of incoming nucleoside triphosphates (releasing PPi)

Answer 1

DNA polymerization is energized by the hydrolysis of incoming nucleoside triphosphates (releasing PPi). The energy released from this hydrolysis reaction is used to form the phosphodiester bond between the incoming nucleotide and the growing chain. Hence the correct answer is option C

Step-by-step explanation:

DNA polymerization is energized by the hydrolysis of incoming nucleoside triphosphates (releasing PPi). When the bond between the phosphates is broken, the energy released is used to form the phosphodiester bond between the incoming nucleotide and the growing chain. This energy is obtained from the high-energy bonds in the nucleoside triphosphates, just like in ATP hydrolysis.

Hence the correct answer is option C