Question

You are interested in a soluble protein that functions within the ER lumen named Fuzzy, Given that info, which of the following statements must be true?

a)Fuzzy has a c-term signal sequence that binds to SRP
b)Only one ribosome can be bound to the mRNA encoding fuzzy during translation
c)fuzzy must contain a hydrophobic stop-sequence
d) once the signal sequence from fuzzy has been cleaved, the signal peptide will be ejected into the ER membrane and degraded

Answer 1

The correct statement is that once the signal sequence from the protein Fuzzy has been cleaved, the signal peptide will be ejected into the ER membrane and degraded.

Step-by-step explanation:

The correct statement among the given options is d) once the signal sequence from fuzzy has been cleaved, the signal peptide will be ejected into the ER membrane and degraded.

In the process of protein synthesis in the endoplasmic reticulum (ER), proteins that are targeted to the ER lumen contain signal peptides at their N-terminus. The signal sequence binds to an SRP (signal recognition particle) and guides the ribosome to the ER membrane. Once the signal sequence is cleaved, the signal peptide is ejected into the ER membrane and degraded.