Final answer:
Ganglionic synapses in both divisions of the ANS use acetylcholine with nicotinic cholinergic receptors, making the statement True. Nicotinic receptors cause depolarization when ACh binds to them, while postganglionic neurons release different neurotransmitters depending on the division.
Step-by-step explanation:
The question pertains to whether ganglionic synapses in both divisions of the autonomic nervous system (ANS) use acetylcholine (ACh) as neurotransmitters with nicotinic cholinergic receptors. The answer to this question is True. Both the sympathetic and parasympathetic divisions have ganglionic neurons activated by ACh released from preganglionic fibers. These neurons have nicotinic receptors, which are ligand-gated ion channels that lead to the depolarization of the neuron when ACh binds to them. It's important to note that while preganglionic fibers in both divisions release ACh, the postganglionic fibers release different neurotransmitters: norepinephrine for the sympathetic (with the exception of sweat glands and blood vessels associated with skeletal muscles which release ACh) and ACh for the parasympathetic, which then act on muscarinic receptors.