Final answer:
Fine-needle aspirate is the sampling technique that collects many cells from the tissue in lesions that yield few cells.
Step-by-step explanation:
The sampling technique that has the advantage of collecting many cells from the tissue, especially in lesions that are firm and yield few cells, is fine-needle aspirate.
Fine-needle aspirate involves inserting a thin needle into the tissue and extracting cells for examination. This technique allows for the collection of a larger number of cells compared to other techniques such as scraping, imprinting, or swabbing.