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Which of the following distinguishes between regenerative and nonregenerative anemia?

1) Erythrocyte morphology
2) Bone marrow response
3) Etiology
4) Erythrocyte indices

1 Answer

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Final answer:

The difference between regenerative and nonregenerative anemia lies in the bone marrow's response, with regenerative anemia showing compensation through increased RBC production and nonregenerative anemia showing inadequate bone marrow response.

Step-by-step explanation:

The primary distinction between regenerative anemia and nonregenerative anemia is the bone marrow response. Regenerative anemia is characterized by increased production of red blood cells (RBCs) as evidenced by a higher reticulocyte count, which reflects the bone marrow's attempt to compensate for the anemia. In contrast, nonregenerative anemia demonstrates a lack of increased RBC production, with low reticulocyte counts indicating insufficient or failed bone marrow response.

Anemias can broadly be categorized based on their causes such as blood loss, faulty or decreased RBC production, or excessive destruction of RBCs. Evaluating bone marrow response is a crucial factor in the kinetic approach to diagnosing anemias. Key tests like erythrocyte indices and reticulocyte counts help distinguish between different types of anemias, providing insights into the bone marrow's capacity to produce RBCs.

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