Final answer:
Cell-mediated immunity is more likely to defend against virally-infected cells, cancer cells, and transplanted tissue.
Step-by-step explanation:
Cell-mediated immunity is more likely to defend against virally-infected cells, cancer cells, and transplanted tissue compared to humoral immunity.
The cell-mediated immune response involves mainly T cells, including cytotoxic T cells, which are responsible for destroying cells infected with viruses and some cancer cells. This type of immune response is also involved in rejecting transplanted tissue.
On the other hand, humoral immunity, which involves mainly B cells, is primarily concerned with fighting pathogens in extracellular spaces by releasing antibodies. However, it cannot effectively target intracellular pathogens like viruses and cancer cells.