Final answer:
The most suitable response based on the transtheoretical model of change is to validate the patient's feelings and ask about their challenges in quitting smoking.
Step-by-step explanation:
The most appropriate response to a patient who states, 'Me, stop smoking? I've been smoking since I was 16!' is option 3: 'I understand. Can you think of the greatest reason why stopping smoking would be challenging for you?'
This response is in line with the transtheoretical model of change, which recognizes that individuals go through different stages of readiness to change.
By acknowledging the patient's resistance and asking for their perspective, the healthcare provider is fostering self-reflection and exploring the individual's motivation for cessation.
correct option 3). " I understand. Can you think of the greatest reason why stopping smoking would be challenging for you?"