Final answer:
The synonym for 'despicable' from the provided options is 'vile,' which similarly denotes something unpleasant and morally wrong.
Step-by-step explanation:
The synonym for despicable in the list provided is vile. Both words are adjectives that describe something as extremely unpleasant, morally reprehensible, or morally wrong, hence sharing a similar meaning. The word base also has a similar meaning in some contexts but is a less common synonym. Meanwhile, laudable and worthy are antonyms of despicable; they describe something that deserves praise or is honorable, respectively.