Question

PI 3-kinase phosphorylates a lipid in the plasma membrane.
a-true
b-false

Answer 1

Phosphoinositide 3-kinase (PI 3-kinase) does not phosphorylate a lipid in the plasma membrane. Instead, it phosphorylates the 3-position of the inositol ring in phosphatidylinositol (PI) lipids, producing phosphatidylinositol-3-phosphate (PIP3).

Step-by-step explanation:

False.

Phosphoinositide 3-kinase (PI 3-kinase) does not phosphorylate a lipid in the plasma membrane. Instead, PI 3-kinase phosphorylates the 3-position of the inositol ring in phosphatidylinositol (PI) lipids, producing phosphatidylinositol-3-phosphate (PIP3). PIP3 serves as a critical second messenger that plays a role in various cellular processes, including cell growth, proliferation, and survival.