Question

DNA microarrays may be paired with chromatin immunoprecipitation (ChIP) to:

a) Assay the use of substrates by different enzymes
b) Determine mRNA folding patterns
c) Identify DNA sequences bound by specific proteins
d) Identify protein-protein interactions

Answer 1

DNA microarrays coupled with chromatin immunoprecipitation (ChIP) are used to c) identify DNA sequences bound by specific proteins. Hene, c) is correct.

Step-by-step explanation:

DNA microarrays can be paired with chromatin immunoprecipitation (ChIP) to identify DNA sequences bound by specific proteins. This technique involves isolating the DNA sequences that are bound to a particular protein by immunoprecipitating the protein.

The fragments are then hybridized to a microarray, allowing researchers to determine the occupancy of protein binding sites throughout the genome.