Final answer:
Elevated glucocorticoid levels during stress may explain various effects such as loss of cells in the amygdala, memory problems in older persons, poor performance in tasks of cocaine self-administration, induction of Alzheimer's disease, and inhibition of growth.
Step-by-step explanation:
Glucocorticoids, such as cortisol, are hormones released during stress that can have various effects on the body. Elevated glucocorticoid levels during stress may explain the following:
- Loss of cells in the amygdala: Chronic stress and high glucocorticoid levels have been associated with the loss of neurons in the amygdala, a brain region involved in emotional processing.
- Development of memory problems in older persons: Prolonged exposure to high glucocorticoid levels can impair memory function, particularly in older individuals.
- Poor performance of stressed rats in tasks of cocaine self-administration: Stress and glucocorticoids can interfere with the reward system in the brain, leading to changes in behavior and reduced motivation.
- Induction of Alzheimer's disease after stress: There is evidence suggesting that chronic stress and elevated glucocorticoid levels may contribute to the development or progression of Alzheimer's disease.
- The inhibition of growth noted during stress: Glucocorticoids have catabolic effects on tissues, including muscle proteins, and can inhibit growth processes.