Final Answer:
The true statement about the spread of sexually transmitted infections, including HIV, is:
4) It is at least twice as easy for a male to infect a female as for a female to infect a male.
Step-by-step explanation:
Paraphrase from the question: The statement acknowledges that the spread of STIs, including HIV, is more likely from males to females compared to females to males.
This option indicates that the transmission of STIs, including HIV, is more efficient from males to females than the reverse.
This aligns with the biological and anatomical factors that may contribute to a higher transmission risk from the males to females.
The true statement about the spread of sexually transmitted infections, including HIV, is:
4) It is at least twice as easy for a male to infect a female as for a female to infect a male.