Final answer:
Christopher Columbus's second voyage to the Americas was to establish Spanish colonies on the islands of the Caribbean.
Step-by-step explanation:
The purpose of Christopher Columbus's second voyage to the Americas was to establish Spanish colonies on the islands of the Caribbean. After his initial voyage, Columbus believed he had reached the Indies and returned to Spain with enough wealth and valuables to secure permission for a second voyage. His goal was to establish settlements and secure the newly discovered lands for Spain.