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A 26-year old multigravida is 14 weeks' pregnant and is scheduled for an alpha-fetoprotein test. She asks the nurse, "What does the alpha-fetoprotein test indicate?" The nurse bases a response on the knowledge that this test can detect:

1) Kidney defects
2) Cardiac defects
3) Neural tube defects
4) Urinary tract defects

1 Answer

3 votes

Final answer:

The alpha-fetoprotein test is primarily used to screen for neural tube defects in the fetus, such as spina bifida and anencephaly, by measuring the levels of AFP in the mother's blood. The correct option is 3.

Step-by-step explanation:

The alpha-fetoprotein test (AFP) is a prenatal screening test that helps to detect certain fetal conditions, primarily neural tube defects such as spina bifida and anencephaly. It is also used in screening for other conditions, including chromosomal abnormalities and abdominal wall defects in the fetus.

The AFP test measures the levels of alpha-fetoprotein in the mother's blood during pregnancy, which can provide indirect evidence of the fetus's health status. AFP is produced by the fetus and can enter the mother's bloodstream via the placenta. Abnormal levels of AFP could indicate the possibility of a defect, but further diagnostic follow-up such as amniocentesis may be recommended for a more definitive assessment.

While the AFP can be an indicator for the health of the kidneys and the urinary tract, as these organs are also involved in the production and release of alpha-fetoprotein into the amniotic fluid and subsequently the mother's blood, the test is primarily associated with neural tube defects when discussing what it indicates. It is not typically used to directly detect kidney defects, cardiac defects, or urinary tract defects. For these, other specific tests and monitoring would be required throughout the pregnancy.

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