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What are the types of receptors involved in metabotropic/neuromodulatory signaling?

1) Ionotropic receptors
2) Metabotropic receptors
3) Neuromodulatory receptors
4) Both B and C

1 Answer

2 votes

Final answer:

In metabotropic/neuromodulatory signaling, the types of receptors involved are metabotropic receptors and neuromodulatory receptors. Metabotropic receptors involve a G protein and lead to metabolic changes in the cell, while neuromodulatory receptors influence neurotransmitter effects, making 'both B and C' the correct answer to the student's question.

Step-by-step explanation:

The types of receptors involved in metabotropic/neuromodulatory signaling are metabotropic receptors and neuromodulatory receptors. Metabotropic receptors are part of a complex that causes metabolic changes within the cell upon neurotransmitter binding. They involve a transmembrane receptor protein, a G protein, and an effector protein. The G protein activates the effector protein, which then generates a second messenger such as cAMP, leading to further cellular changes. Neuromodulatory receptors, as the name suggests, are part of the modulatory signaling pathways in the nervous system, often influencing the effects of neurotransmitters rather than directly triggering post-synaptic responses.

Ionotropic receptors, conversely, are ligand-gated ion channels that open promptly when a neurotransmitter binds, allowing ions to flow across the membrane, resulting in a fast post-synaptic response. Therefore, for the question regarding metabotropic/neuromodulatory signaling, the correct answer is both B and C, referring to metabotropic and neuromodulatory receptors.

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