Question

What effect does the binding of the SRP to the growing polypeptide chain and the ribosome have?

1) the ribosomes attaches to the RER
2) Protein synthesis is accelerated
3) The ribosomes attaches to the Golgi complex
4) Protein synthesis is terminated
5) The ribosome dissociates

Answer 1

The SRP binds to the growing polypeptide, halting synthesis, guides the ribosome to the RER, and detaches to allow protein synthesis to resume with the ribosome now on the RER for proper protein targeting and processing.

Step-by-step explanation:

The binding of the SRP (signal recognition particle) to the growing polypeptide chain and the ribosome results in a temporary halt in protein synthesis. This pause in elongation allows the SRP-ribosome complex to locate and bind to an SRP receptor on the membrane of the Rough Endoplasmic Reticulum (RER). The SRP then detaches, and protein synthesis resumes with the ribosome now attached to the RER. This process facilitates the co-translational import of the growing polypeptide into the lumen of the RER, where it begins to fold and potentially undergoes modification. This careful coordination ensures proteins destined for secretion or for the membrane are properly targeted and processed.