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During what division can prophase be broken into substages?

User Zelf
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Final answer:

Prophase can be broken into substages including nuclear envelope breakdown, chromatin condensation, centrosome migration, and spindle formation.

Step-by-step explanation:

In mitosis, prophase is the first phase and can be further divided into substages. The substages of prophase are:

  1. Nuclear envelope breakdown: The nuclear envelope starts to break into small vesicles.
  2. Chromatin condensation: The loosely packed chromatin coils and condenses into visible chromosomes.
  3. Centrosome migration: The centrosomes begin to move to opposite poles of the cell.
  4. Spindle formation: The microtubules that form the mitotic spindle extend between the centrosomes.

These substages occur sequentially during prophase.

User Lnu
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