Final answer:
General transcription factors recruit RNA polymerase to the TATA box and other regulatory elements at the promoter, while specific transcription factors bound to enhancer regions help augment or prevent transcription.
Step-by-step explanation:
To start transcription, general transcription factors, such as TFIID, TFIIB, and others, must first bind to the TATA box and recruit RNA polymerase to that location. Additional transcription factors may also bind to other regulatory elements at the promoter to increase or prevent transcription. In addition to promoter sequences, enhancer regions help augment transcription. Enhancers can be upstream, downstream, within a gene itself, or on other chromosomes. Specific transcription factors bound to enhancer regions may either increase or prevent transcription.