Final answer:
The TRUE statement about HSP70-type molecular chaperones is that they assist in protein folding and preventing misfolding. These chaperones are crucial in stabilizing proteins under normal and stress conditions, and are present in multiple cellular compartments, not just during mitosis or exclusively in the nucleus. Option c.
Step-by-step explanation:
The statement regarding HSP70-type molecular chaperones that is TRUE is: C) HSP70 chaperones assist in protein folding and preventing misfolding.
HSP70 chaperones are an essential component of cellular function as they help in the correct folding of proteins, which is critical for their proper function. These chaperones work by stabilizing unfolded or partially folded proteins, preventing them from aggregating, and assisting them to reach their native and functional three-dimensional structure. This process is particularly important under stress conditions where proteins are more prone to misfolding, such as high temperature or abnormal pH levels.
While they were initially discovered in response to heat shock, which is when cells elevate the synthesis of these proteins to protect against thermal-induced protein damage, HSP70 chaperones are active under normal cellular conditions as well. They are not only found in the nucleus but also in various cellular compartments like the cytoplasm and mitochondria, and their function is not limited to the mitotic phase of the cell cycle.