Final answer:
The Avery, MacLeod, and McCarty Experiment demonstrated that DNA was the genetic material responsible for transformation, as only the degradation of DNA could prevent the transformation of R strain bacteria.
Step-by-step explanation:
The Avery, MacLeod, and McCarty Experiment determined that the only way to eradicate transformation was to degrade the DNA. Scientists Oswald Avery, Colin MacLeod, and Maclyn McCarty conducted experiments that followed up on Frederick Griffith's work with the transforming principle. They used specific enzymes to degrade proteins, RNA, and DNA within heat-killed S strain of bacteria. Their results showed that only when DNA was destroyed could the transformation of R strain bacteria be prevented, leading to the conclusion that DNA was indeed the substance responsible for transformation. This pivotal experiment provided strong evidence that DNA was the genetic material responsible for heredity.