Final answer:
The plus end of microtubules is oriented away from the centrosome.
Step-by-step explanation:
When microtubules grow out of a centrosome, the end that is oriented away from the centrosome is the plus end.
Microtubules grow by adding more tubulin subunits, similar to adding more links to a chain. The plus end of microtubules is where new tubulin subunits are added, allowing the microtubule to grow.