Question

Which of the following is one way in which a misfolded protein might be recognized by the protein surveillance machinery of the cell?

1) By binding to chaperone proteins
2) By undergoing degradation by the proteasome
3) By being transported to the endoplasmic reticulum
4) By forming aggregates with other misfolded proteins

Answer 1

Misfolded proteins can be recognized by the cell's protein surveillance machinery by binding to chaperone proteins. Chaperones assist proteins in folding correctly, preventing misfolding or aggregation. By binding to chaperone proteins, misfolded proteins can be repaired or targeted for degradation.

Step-by-step explanation:

One way in which a misfolded protein might be recognized by the protein surveillance machinery of the cell is by binding to chaperone proteins. Chaperones assist proteins in folding correctly, preventing them from misfolding or aggregating. These chaperone proteins help guide the misfolded protein into the correct folding pathway, allowing it to adopt its functional conformation. By binding to chaperone proteins, the misfolded protein can be repaired or targeted for degradation, ensuring cellular homeostasis and preventing the accumulation of toxic aggregates.