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Why is SyBr green less toxic than EtBr?

User Hadia
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Final answer:

SyBr Green is less toxic than EtBr due to differences in cellular uptake and environmental persistence. Although less toxic, caution should still be exercised when handling both substances.

Step-by-step explanation:

SyBr Green is less toxic than EtBr because it is not as readily absorbed by living cells. EtBr is able to enter cells through passive diffusion and bind to DNA, while SyBr Green has a larger molecular structure that prevents it from easily entering cells. This difference in cellular uptake contributes to the lower toxicity of SyBr Green. Another reason for the lower toxicity of SyBr Green is that it is not as persistent in the environment. EtBr is known to be persistent and can accumulate in the environment over time, increasing the potential for harm. SyBr Green, on the other hand, breaks down more quickly and is less likely to accumulate in the environment. It's important to note that while SyBr Green is less toxic than EtBr, it is still important to handle both substances with care and follow proper safety protocols when working with them.

User JLTChiu
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