124k views
3 votes
Which is true of antibodies to the Kidd blood group system antigens?

1) They are enhanced by enzymes
2) They quickly drop below detection limits
3) They are high titer low avidity (HTLA) antibodies
4) They can be neutralized with urine

1 Answer

6 votes

Final answer:

Antibodies to the Kidd blood group system antigens can be neutralized with urine because they can bind to soluble forms of the antigen present in it. They are not high titer low avidity antibodies, nor are they enhanced by enzymes.

Step-by-step explanation:

When considering the characteristics of antibodies to the Kidd blood group system antigens, the correct statement is: they can be neutralized with urine. This peculiar characteristic is due to the presence of soluble forms of the antigen in the urine, which can bind to these antibodies, thereby preventing them from reacting with the red blood cells. This is relevant in the context of transfusion medicine, as the Kidd system antigens Jka and Jkb are of clinical significance.

Though antibodies to the Kidd blood group system may decrease in detectability over time and are indeed capable of causing delayed hemolytic transfusion reactions, they are not categorized as high titer low avidity (HTLA) antibodies, nor are they specifically enhanced by enzymes. Detecting Kidd antibodies can be challenging due to their characteristic of sometimes becoming undetectable, which requires clinical vigilance.

User Falco
by
7.2k points