Final answer:
Anti-D is considered an autoantibody when found in the plasma of an adult who should not normally have this antibody, suggesting an autoimmune response.
Step-by-step explanation:
Autoantibodies are antibodies that mistakenly target and react with a person's own tissues or organs. One such antibody that can be considered an autoantibody if found in the plasma of an adult is Anti-D. This antibody can be involved in Rh incompatibility, such as in the case of hemolytic disease of the newborn. However, if an individual is Rh-positive and yet develops Anti-D antibodies, it typically indicates an autoimmune response, a condition where the body's immune system attacks its own cells. Examples of diseases with autoantibodies include myasthenia gravis and systemic lupus erythematosus (SLE).