Final answer:
In the diagram, the letter that corresponds to an ancestor with a nucleus is A.
Step-by-step explanation:
Based on the diagram, the letter that corresponds to an ancestor with a nucleus is A. The presence of a nucleus distinguishes eukaryotic cells from prokaryotic cells. Organisms with a nucleus are part of the domain Eukarya, which includes plants, animals, fungi, and protists.
Therefore, option 4) A is the correct answer.