Question

A patient has a currently nonreactive antibody screen but has a history of anti-Jka in their patient file. Which type of crossmatch must be performed on this patient?

1) Immediate spin crossmatch
2) IAT crossmatch
3) Electronic crossmatch
4) DAT crossmatch

Answer 1

An IAT crossmatch is required for a patient with a history of anti-Jka in their file, even if their current antibody screen is nonreactive, to ensure safe blood transfusion.

Step-by-step explanation:

If a patient has a history of anti-Jka in their patient file but their antibody screen is currently nonreactive, the type of crossmatch that must be performed is an IAT crossmatch (Indirect Antiglobulin Test). The IAT is necessary to screen for antibodies that are unbound in a patient's serum, which includes those against red blood cell antigens other than the A and B antigens.

This is important because the patient's history suggests that they have developed antibodies previously, and although the current screen is nonreactive, it's possible for the anti-Jka to become active again, especially when exposed to transfused red blood cells carrying the Jka antigen.