Final answer:
3. Sampling bias is the bias you need to guard against the most when conducting an opinion poll.
Step-by-step explanation:
In statistics, the bias you need to guard against the most when conducting an opinion poll is 3. sampling bias. Sampling bias occurs when the method of selecting the sample causes it to be unrepresentative of the population being studied. This can lead to incorrect conclusions about the population.
For example, if a survey is conducted only at noon lunchtime, it would not include students who do not have a noon lunchtime, resulting in a biased sample.