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You receive a TPN order for 250 mL consisting of: Aminosyn 5%, and Dextrose 15% with the Additives: KCl 8 mEq, Ca Gluconate 2 mEq and Ped MVI 2.5 mL. You have available in stock: Aminosyn 17%, Dextrose 50% and the Additives: KCl 4 mEq/mL, Ca Gluconate 8.0 mEq/mL and Ped MVI 10mL

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The resulting solution will have the following composition:

  • Aminosyn 5% (125 mL)
  • Dextrose 15% (375 mL)
  • KCl 8 mEq (2 mL)
  • Ca Gluconate 2 mEq (0.25 mL)
  • Ped MVI 2.5 mL

How to prepare TPN solution?

To prepare the TPN solution using the available stock:

Ingredients:

Aminosyn 17%

Dextrose 50%

KCl 4 mEq/mL

Ca Gluconate 8.0 mEq/mL

Ped MVI 10 mL

Calculations:

Aminosyn:

Need 125 mL of Aminosyn 5% in the final solution. To prepare this using Aminosyn 17%, use the following formula:

Volume of Aminosyn 17% = (Desired volume of Aminosyn 5%) × (5% / 17%)

Volume of Aminosyn 17% = (125 mL) × (5% / 17%)

≈ 35.3 mL

Dextrose:

Need 375 mL of Dextrose 15% in the final solution. To prepare this using Dextrose 50%, we can use the following formula:

Volume of Dextrose 50% = (Desired volume of Dextrose 15%) × (15% / 50%)

Volume of Dextrose 50% = (375 mL) × (15% / 50%)

≈ 112.5 mL

KCl:

Need 8 mEq of KCl in the final solution. To prepare this using KCl 4 mEq/mL, use the following formula:

Volume of KCl 4 mEq/mL = (Desired amount of KCl in mEq) / (Concentration of KCl in mEq/mL)

Volume of KCl 4 mEq/mL = (8 mEq) / (4 mEq/mL) = 2 mL

Ca Gluconate:

Need 2 mEq of Ca Gluconate in the final solution. To prepare this using Ca Gluconate 8.0 mEq/mL, we can use the following formula:

Volume of Ca Gluconate 8.0 mEq/mL = (Desired amount of Ca Gluconate in mEq) / (Concentration of Ca Gluconate in mEq/mL)

Volume of Ca Gluconate 8.0 mEq/mL = (2 mEq) / (8.0 mEq/mL) = 0.25 mL

Ped MVI:

Need 2.5 mL of Ped MVI in the final solution. Since there is Ped MVI 10 mL available, use 0.25 mL.

Preparation:

Measure 35.3 mL of Aminosyn 17%.

Measure 112.5 mL of Dextrose 50%.

Measure 2 mL of KCl 4 mEq/mL.

Measure 0.25 mL of Ca Gluconate 8.0 mEq/mL.

Measure 0.25 mL of Ped MVI 10 mL.

Combine all the ingredients in a sterile container and mix thoroughly.

The resulting solution will have the following composition:

Aminosyn 5% (125 mL)

Dextrose 15% (375 mL)

KCl 8 mEq (2 mL)

Ca Gluconate 2 mEq (0.25 mL)

Ped MVI 2.5 mL

User Ole Wolf
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