Final answer:
The most common manifestation of Ewing sarcoma in an adolescent client includes pain in the upper thigh, which corresponds with the growth of the tumor in long bones such as the femur.
Step-by-step explanation:
The student is asking about the clinical manifestations they should anticipate when assessing an adolescent client who has Ewing sarcoma. Among the provided options, symptom number 1 is the most indicative of the condition. Ewing sarcoma commonly presents as bone pain and may cause localized swelling.
It most frequently affects the long bones, such as the femur, which is located in the thigh. Therefore, client reports pain in the upper thigh is a typical manifestation of this type of cancer.