Final answer:
There are 86493225 ways to make a committee of twelve board members.
Step-by-step explanation:
To solve this problem, we can use the concept of combinations. We need to choose 12 board members out of a total of 30 (8 females and 22 males).
The formula for combinations is nCr = n! / (r! * (n-r)!), where n is the total number of items and r is the number of items to be selected.
Using this formula, we can calculate the number of ways to choose 12 board members as:
C(30, 12) = 30! / (12! * (30-12)!) = 86493225
Therefore, there are 86493225 ways to make a committee of twelve board members.