Final answer:
Option 4) They entail the participation of IgE antibodies and the release of histamine from mast cells and basophils.
Step-by-step explanation:
The accurate response is option 4) They entail the participation of IgE antibodies and the release of histamine from mast cells and basophils.
IgE antibodies are involved in allergic reactions and play a central role in the release of histamine from mast cells and basophils. When a person is initially exposed to an allergen, IgE antibodies are synthesized and bind to mast cells. On subsequent exposure to the same allergen, the allergen binds to the IgE antibodies on mast cells, causing the release of histamine and other inflammatory molecules.
This reaction is a type I hypersensitivity reaction, commonly known as an allergic reaction. The release of histamine can lead to symptoms such as itching, swelling, and redness.