Final answer:
Australopithecus afarensis and Homo neanderthalensis had differences in cranial capacity, stature, and tool-making abilities.
Step-by-step explanation:
Australopithecus afarensis and Homo neanderthalensis had several differences in their skulls that can be inferred. First, Homo neanderthalensis had a larger cranial capacity than Australopithecus afarensis, indicating that Neanderthals had a larger brain. Second, while both species were bipedal, Neanderthals had a taller stature compared to Australopithecus afarensis. Lastly, there is no evidence to suggest that Australopithecus afarensis created tools, while Neanderthals were known to have advanced stone tool-making abilities.