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How can one learn about unseen alleles in a child's parents by observing traits in the child?

User Yurilo
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Final answer:

One can learn about unseen alleles in a child's parents by observing the child's traits. If a child expresses a recessive trait, both parents must carry the recessive allele. Autosomal dominant disorders indicate that at least one parent carries the dominant allele.

Step-by-step explanation:

By observing the traits of a child, one can often infer the possible alleles present in a child's parents. This process utilizes Mendel's Theory of Inheritance, which gives a framework for understanding how traits are transmitted from parents to offspring. For example, if a child displays a recessive trait, like albinism, we can deduce that both parents must carry the recessive allele since two copies are required for the trait to be expressed. Similarly, if a child has an autosomal dominant disorder, at least one parent must have the dominant allele causing the disorder. However, due to the randomness in allele segregation and fertilization, the predicted outcome of genetic crosses, like the 3:1 phenotypic ratio seen in Mendel’s pea plant experiments, might not always match actual outcomes in smaller families, as chance plays a larger role. This situation emphasizes the principle that while genetics can provide probable outcomes, it cannot guarantee specific results, especially with a limited number of offspring.

Additionally, advancements such as the sequencing and annotation of the human genome, coupled with studying karyograms, enable geneticists to visually confirm or predict abnormalities. In human genetics, X-linked traits such as hemophilia are passed from mothers to sons with a 100 percent probability that the mother is homozygous for the recessive trait. The use of Punnett squares during genetic counseling can help predict probabilities but does not ensure specific outcomes due to each child's unique combination of alleles from their parents.

User Hss
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