Final answer:
Gender plays a significant role in shaping social differences between individuals based on their assigned biological sex.
Step-by-step explanation:
The statement Anna and John are socially different because of their gender is true. Gender is a social construct that encompasses the roles, behaviors, and expectations society assigns to individuals based on their biological sex. Society generally imposes different norms, expectations, and privileges on males and females, which contribute to their social differences. For example, in many cultures, traditional gender roles assign men as breadwinners and women as caregivers, resulting in different opportunities and experiences for individuals based on their gender.