Question

What were the problems with the research reported in Lancet by Dr. Andrew Wakefield in 1998?

a) The sample size was too small for meaningful conclusions.
b) The study had a conflict of interest as Wakefield was pursuing a vaccine patent.
c) Data manipulation and unethical research practices were involved.
d) The research lacked peer review and replication.

Answer 1

Dr. Andrew Wakefield's 1998 Lancet study had several issues, including a limited sample size, a conflict of interest, data manipulation, a lack of peer review, and replication.

Step-by-step explanation:

The issues with the study that Dr. Andrew Wakefiend published in the Lancet in 1998 were:

1. The sample size was too small for meaningful conclusions.
2. The study had a conflict of interest as Wakefield was pursuing a vaccine patent.
3. Data manipulation and unethical research practices were involved.
4. The research lacked peer review and replication.

The publication was later retracted due to these issues, and it is important to rely on research that undergoes proper scientific scrutiny.