Final answer:
The theme of 'An Uncomfortable Bed' is best encapsulated by the quote 'Paranoia can make fools out of people', which highlights how fear and suspicion can lead to ridiculous situations in comedic storytelling.
Step-by-step explanation:
The quote that best describes the theme of 'An Uncomfortable Bed' would likely be 'Paranoia can make fools out of people'. The story typically revolves around characters finding themselves in absurd situations due to their own fears and suspicions, much like the man who, in anticipation of being pranked, goes through great lengths to avoid it, only to find that his own actions lead to a suitably comic downfall.
In the context of the quotations provided, the selected quote aligns with the narrative that embodies the humor and mishaps driven by the characters' paranoia. Comedies like this one utilize the flawed reasoning and exaggerated behaviors of individuals, leading to humorous outcomes that entertain the audience and also impart a lesson or moral about the human condition.