Final answer:
The backcountry settlers faced conflicts with Native Americans as they traveled along the Appalachian Mountains in search of new lands.
Step-by-step explanation:
The backcountry settlers traveled along the Appalachian Mountains and often fought with the Native Americans. British colonists seeking new lands moved westward over the Appalachians, encountering various Native American tribes. This westward movement, intensified after the French and Indian War, brought settlers into conflict with Native tribes such as the Shawnee, Seneca-Cayuga, Wyandot, and Delaware. This resulted from both the settlers' and the Native Americans' desire to hold on to these lands.