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What is X-inactive specific transcript (XIST)?

User SanBen
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Final answer:

X-inactive specific transcript (XIST) is an IncRNA that forms Barr bodies during X inactivation in female mammals. The inactive X chromosome does not express its genes, compensating for the double genetic dose in females.

Step-by-step explanation:

X-inactive specific transcript (XIST) is a recently discovered IncRNA that plays a crucial role in the process of X inactivation in female mammals. XIST is required to form Barr bodies, which are condensed structures that form when one of the X chromosomes in somatic cells is inactivated. The genes on the inactive X chromosome are not expressed, allowing females to compensate for their double genetic dose of X chromosome.

User Berry Boessenkool
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