Question

Mutations in the _____ gene prevent suppression of the cell cycle

a.p53
b.ras
c.BRCA1
d.telomeres

Answer 1

Mutations in the a) p53 gene prevent suppression of the cell cycle. The p53 protein is an important tumor suppressor gene that plays multiple roles in the cell cycle. Hence, a) is correct.

Step-by-step explanation:

Mutations in the p53 gene prevent suppression of the cell cycle. The p53 protein is an important tumor suppressor gene that plays multiple roles in the cell cycle.

A cell with a faulty p53 gene may fail to detect errors in the DNA and cannot signal the necessary DNA repair enzymes, leading to uncorrected damaged DNA. Furthermore, the mutated version of p53 found in cancer cells cannot trigger cell death.