Final answer:
The CISO should target the project management office to integrate security from the start of IT projects, ensuring a rapid and foundational spread of security measures across the business.
Step-by-step explanation:
The CISO should prioritize targeting the project management office first to embed security across the business effectively and swiftly. By ensuring security considerations are included at all levels of the project management process, the CISO can achieve rapid transformation and risk mitigation across new and in-progress IT projects.
This approach leverages existing workflows and maximizes the impact of security measures by integrating them into the foundation of IT project structures. Addressing project management processes secures the organization from the beginning of any technology deployment or change, rather than retrofitting security as an afterthought—thus aligning with the principle of 'secure by design.'
Furthermore, this direction ensures that all involved parties, from programmers to risk assurance teams, understand their role in the security landscape from the outset, streamlining the implementation of secure practices across the organization.