Final answer:
The most effective procedure for collecting a serum blood sample from a canine is to collect the blood into a tube containing lithium heparin and centrifuge it to obtain plasma.
Step-by-step explanation:
The most effective procedure when collecting a serum blood sample from a canine is to collect the blood into a tube containing lithium heparin and centrifuge it to obtain plasma. This process separates the blood cells from the plasma, allowing for the collection of serum. Serum is the liquid component of the blood that remains after the clotting process, and it is rich in antibodies and other proteins that can be analyzed.