A catalyst speeds a reaction because it reduced the transition energy and in turn lowers the activation energy. Therefore taking this into consideration we can proceed to analyze each available option.
a. reducing the overall temperature. This is not correct as the temperature does not depend on the catalyst.
b. destabilizing bonds in the substrate. This is not correct as this depends on the reaction.
c. changing the order of amino acids. This is not correct as amino acids have a specific order in proteins and are built by ribosomes.
d. adding energy to the substrate. This is correct, more than adding energy facilitates the process due to a reduction in the transition energy.
e. all of the above. This is not correct as many of them are incorrect too.